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Immunoprecipitation and fluorescence resonance energy transfer assays demonstrated that the presence of different fluorescent protein markers at the C-termini of individual α chains neither altered formation of triple-helical molecules nor affected their secretion to the extracellular space.
To evaluate the effect of Meis1 on epithelial morphology, the uteri of these mice were examined with scanning electron microscopy for evidence of altered formation of pinopodes.
Moreover, we will discuss the potential mechanisms by which defects in neurogenesis and neurodegenerative processes lead to altered formation of neural circuits and impair cognitive function, in connection with findings on pharmacological treatments of potential benefit for DS.
Patients with SLE exhibited an altered formation of FXIIa complexes.
Expression of the 473HD epitope was shown to be decreased in the neural stem cells of D4st1−/− mice, and this resulted in the altered formation of neurospheres [ 96].
In response to their surroundings, particular species can occur in alternative phenotypes, and these can result in the altered formation of metabolites and/or products.
Similar(53)
Δ12-PGJ2 increased formation of phospho- T308 Akt phospho- T308 Aktformation of phospho-(S241)PDK1 (the kinase that phosphorylates T308 of Akt), and without altering PTEN protein expression (formation).
We therefore investigated whether p85α mutants that alter formation of p85α homodimers and/or PTEN binding affect PTEN ubiquitination and stability.
As the interaction with Ub delays Josephin aggregation but does not suppress it altogether, we finally explored whether addition of Ub alters formation of the mature fibers and/or changes their morphology.
The keratinocyte maturation is altered with formation of xerosis represented by a more compact aspect of corneocyte clumps.
In agreement with this view, we found that the suppression of TBPH in the glia altered the formation of evoked synaptic potentials at the NMJ, without affecting the cycle of vesicle release in the presynaptic membranes.
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