Sentence examples for altered flexibility from inspiring English sources

Abnormal bone turnover in OA leads to a zone of osteoporosis beneath the thickened subchondral plate, altered flexibility, and increased microfracture [ 4].

Pollak's group have provided further evidence that the physicochemical characteristics of actin fibres formed with the mutant alpha-actinin IV show altered flexibility that can explain the effects on the podocyte [ 11].

We hypothesize that the variation of potential distribution, observed in N/N-LOX-1, is due both to an unbalanced network of charges and to an altered flexibility of the basic spine residues that, together, induce a marked inhibition of ox-LDL recognition.

The D175N mutation has shown no change in stability and is therefore not predicted to alter flexibility.

In the case of indels that do not affect structural composition of the protein, they may alter flexibility of the existing protein fold in terms of positioning of structural elements relative to each other or to binding partners.

Chapman-Smith and Whitelaw found that that the region between Helix 2 and the PAS domain in Arnt and AhR shows conformational flexibility [21]; by replacing the PAS domain with the C/EBP leucine zipper, our design may have deleteriously altered the flexibility intrinsic to Arnt at the protein-protein interface.

At intermediate filler content, interparticle interactions appear to dominate, leading to altered polymer flexibility, higher permittivity and lower glass transition temperature.

He said the growth and stability pact - which limits deficits to 3% and debt to 60% of GDP - would not be altered but flexibility would be explored in order to boost growth.

This substitution is highly likely to have altered the flexibility between, or self-association of, two homotypic EDs.

Additionally, we calculated the change in root-mean-square fluctuation of all Cα atoms as a measure of altered backbone flexibility following mutation according to ΔRMSF = RMSF (mutant) — RMSF (wild-type).

The altered conformational flexibility, the degree of correlated motion between residues in the Fas DD, hydrogen bond formation within the CaM binding region, the contact number of each residue, and the electrostatic potential for the CaM binding region caused by the Fas DD V254N mutation could influence the van der Waals interactions and electrostatic interactions between CaM and the Fas DD.