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Other effects may be felt in more indirect ways, such as through altered exposures to chemicals and pathogens whose use and spread, respectively, may shift in response to climate change.
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In rats, this altered exposure to reproductive hormones produces accelerated reproductive aging and a hormonal environment that is conducive to mammary tumor development.
The hypothesis of a causal relation would be supported if an altered exposure to cigarette smoke, for example smoking cessation, could be shown to reduce the risk of stillbirth.
In conclusion, we have shown that the prolonged circulation of SN-38 at low concentrations following CPT-11 administration has clinical implications, and resulted in altered exposure-toxicity relationships.
The hygiene hypothesis concedes that current hygiene practices lead to reduced or altered exposure of bacteria and other micro-organisms that may result in an imbalance of the immune system and microflora early in life.
Inconsistencies may result from different social trends that alter exposures in more than one direction.
To protect children's health, it is prudent to initiate programs designed to alter exposure to well-established leukemia risk factors rather than to suspend judgment until no uncertainty remains.
It was concluded that coadministered ritonavir and PA interact to alter exposure to artesunate, DHA, and ritonavir itself.
Changing the year (1990) or location (MacArthur Airport) of meteorological data collection for a sensitivity analysis did not appreciably alter exposure estimates (Beyea et al. 2005).
Because we cannot definitely rule out a potential role of SULT1A1 in the metabolism of oestrogens, we analyzed our data also with respect to use of oral contraceptives and various reproductive factors that may alter exposure to oestrogens.
These interventions may be characterised as those that affect the sources of pollutants, those that improve the indoor environment, those that alter exposure through behavioural interventions and those of a financial or regulatory nature.
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