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Since some L1 ORF1p mutant proteins, in which neither the binding affinity for RNA nor the RNP formation have been altered, exhibit a reduced retrotransposition rate [ 10, 32], it has been suggested that this protein having NAC activity should have an additional function in the TPRT mechanism at a subsequent step of that involving the RNP formation.
The 3D shape of the mouse node is thought to be important for the establishment of the left right body plan (Cartwright et al., 2004), and mouse mutants, in which the shape of the node is altered exhibit randomized left right body plan (Lee and Anderson, 2008; Lee et al., 2010).
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Since then the Foundation has altered exhibits and tour commentary to reflect Jefferson's paternity of all Hemings' children and has sponsored new research into the interracial society of Monticello and Charlottesville.
In those areas, altered hyaloclastites exhibit a wide range of permeability, from 1°10−17 and 1.5°10−11 m2, positively correlated to the porosity (Frolova et al. 2005).
GE plants or animals have had their genetic makeup altered to exhibit traits that are not naturally theirs.
Approximately 60 ~ 70% of the significantly altered genes exhibited up-regulation after the mutation of prg-1.
"Round", resulted in plant that was further analyzed due to the altered phenotype exhibited in all of its fruits.
One intriguing finding from all of these manuscripts is that cells lacking Sirt3 exhibited altered mitochondrial metabolism as exhibited by increased mitochondrial ROS and superoxide levels during stress.
DOI: http://dx.doi.org/10.7554/eLife.02981.003 10.7554/eLiFigure81 figuregure 1—figure supplement 1. Mice with altered LMNB1 levels do not exhibit altered behavioral rhythms.
mnb mutants exhibit altered synaptic growth and morphology, as well as impaired synaptic vesicle endocytosis.
Latently infected CD4+ TCM cells exhibit altered phosphorylation signatures relative to uninfected cells following T cell activation.
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