Sentence examples for altered cell cycle from inspiring English sources

Moreover, EBAs altered cell cycle progression in breast cancer cell lines in a manner similar to E2 ER.

Under these conditions, cells over-expressing ABF2 proliferate faster and have altered cell cycle progression [5].

Dicer-null NS cells underwent normal self-renewal and could be maintained in vitro indefinitely, but had subtly altered cell cycle kinetics and abnormal heterochromatin organisation.

Depletion or overexpression of ASF1 results in severe developmental defects, altered cell cycle progression and cell death [5], [7], [10], [15], [17].

Thus, we expressed M3-APC in HCT116βw cells (HCT116 cells that contain only a wild-type allele of β-catenin) to determine whether this expression altered cell cycle progression.

Interestingly, FLAG-Tim (Δ1 250) and Tim (Δ250 500) transfected cells had altered cell cycle profiles, suggesting the Tim amino terminal region is important for both Plk1 binding and proper execution of cell cycle events (Fig. S2B).

Thus, oncogenic versions of c-Myb may have altered cell cycle-dependent activities, which could be the key to their transforming activities.

The short variant of the protein, Lyp2 (corresponding to PTPN22_v4), lacks the consensus motif for CDK1, implying altered cell cycle-related regulation of this transcript in lymphoid cells compared to Lyp1 [ 3].

Cells depleted for NORAD or RBMX display an increased frequency of chromosome segregation defects, reduced replication-fork velocity and altered cell-cycle progression which represent phenotypes that are mechanistically linked to TOP1 and PRPF19 CDC5L function.

This finding is in keeping with a growing body of papers showing that altered cell-cycle status can contribute significantly to neurodegenerative disease.

This suggests that the deregulation of BRCA1 observed in this study is not a simple consequence of altered cell-cycle regulation.