Sentence examples for altered by single from inspiring English sources

As a major deficiency, only genes that are subject to multiple levels of biological regulation are likely to be determined by this approach than genes that are primarily altered by single alteration like amplification or over expression.

We have found that although protein stability can be altered by single amino acid substitution, evolution for optimal function requires more subtle and delocalized mechanisms.Recent results implicate structure in the unfolded state as playing an important and novel role for the thermostability of these proteins.

Moreover, examples that this specificity can be altered by single point mutations have been described [19].

Our results show that S. cerevisiae produce and inactivate PEA, and that this process is significantly altered by single gene deletions or heterologous expression of mammalian proteins involved in neurodegenerative diseases.

This concern could be addressed by determining whether eNOS acetylation level is indeed altered by single allele deletion of SIRT1 in their mouse model in the future experiments.

In the present study, we have shown that the pH sensitiveness and ethylene glycol permeability of DrAqp3b can be altered by single or triple point mutations in its amino acid sequence.

Considering that in total five serines and four threonines were identified to be phosphorylated, it was conceivable that the overall phosphorylation level of EB1 was not significantly altered by single-site or single-motif mutations.

The functions of TNF-α may be altered by single-nucleotide polymorphisms (SNPs) in its gene structure.

On the other hand, translation may be affected by RNA secondary structure which, like splicing, mRNA stability, or other less well understood RNA functions, may be significantly altered by single-nucleotide changes.

This proposition is supported by robust evidence that social networks strongly affect social norms, and that within a network, norms may be altered by a single individual and perpetuated by other network members.

Subroutines are altered by a single punch.