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To verify behavioral phenotypes, genotypes displaying altered behavior were produced from new crosses and subject to identical retests.
Accordingly, to investigate whether loss of Wfs1 in the mPFC of Wfs1 mPFC.KO mice altered behavior in response to stress, a battery of behavioral tests was employed.
These genetically modified mice show changes in gene expression in particular brain regions and altered behavior.
We hypothesize that neuronal-glial interactions, mediated by cytokines, contribute to altered behavior during immune challenges.
"I'd want to know more about the mechanism" by which the bacteria altered behavior in the mice before beginning to translate the findings to humans, he says.
Takeuchi et al report altered behavior in a Dg hypomorph with a higher metabolic rate [25].
At 6 months post-BCAS, the mice were tested for altered behavior.
Although early studies of the behavior of Prnp knockout mice described minor changes, later studies report altered behavior.
Although early studies of the behavior of Prnp knockout mice described only minor changes [5], later studies reported that these mice develop an age-dependent impairment in memory consolidation, altered behavior and neurotransmission (see [6], [7] for reviews).
A growing number of studies have shown that environmental factors including stress, maternal care, and exposure to psychostimulants epigenetically modulate gene expression through chromosomal modification, resulting in altered behavior [1] [3].
Alternatively, altered behavior in diseased lynx could influence exposure to infection.
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