Sentence examples for altered base from inspiring English sources

Synonymous mutations can affect the stability of mRNA secondary structure through altered base pair interactions.

The mutant tRNAs selected by the method included molecules containing novel base substitutions as well as extensively altered base combinations that would not be readily generated by rationally designed site-directed mutagenesis.

Our model hypothesizes that point mutations, which altered base compositions (i.e., GC-to-AT or AT-to-GC), took place before the occurrence of gBGC.

However, when the lesion is in the template strand in the form of a chemically altered base, the exonuclease has no access to the lesion, resulting in a fruitless cycle of DNA synthesis and removal by Pol III and the exonuclease, respectively.

In the case of RNA molecules that bind target RNA segments, such as microRNAs (miRNAs), the altered base pairing can change binding specificities.

Most notably, we observed that more than 70% of the genes that are identified as significantly altered based on copy number alterations (see Methods) are not annotated in current pathway databases (Additional file 1: Figure S1).

The base-excision repair process protects genomes by removing and replacing altered bases in DNA.

But "the civil nature of a confinement scheme cannot be altered based merely on vagaries in the implementation of the authorizing statute," the court said today in an opinion by Justice Sandra Day O'Connor.

In the second before the football is snapped and the second afterward, defensive formations are analyzed, pass routes are altered based on those reads, and nuances change the positioning of every receiver in the scheme.

"I can tell you there have been several patients I've had where their therapy was altered" based on the test results, said Dr. F. Anthony Greco, director of the Sarah Cannon Cancer Center in Nashville and a leading expert on cancer of unknown primary, or CUP, as the mysterious disease is formally known.

Taken together, it is possible that the sperm epigenome can be altered based on lifestyles and various exposures that can accumulate over time and that these alterations have the potential to impact fertility, embryogenesis, and offspring phenotype.