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Olsen liked the house enough to make it his principal home but found it in some ways unlivable and began making alterations within a year after its completion.
In these classes, some tumor types have become easier to treat with the advent of specific biological markers and drugs aimed at alterations within a subtype.
Even a local, calibrated porosity permeability model is associated with an uncertainty range owing to the variations in lithology and diagenetic alterations within a limited local region (geological province).
Cancer is one of many diseases that arise from multiple genetic and epigenetic alterations within a cell [2], [46], [47], [48].
Clonal heterogeneity is defined as the presence of several subclones possessing different genomic alterations within a tumor.
Using the poikilotherm Drosophila, we show that acute temperature alterations within a normal physiological range result in substantial changes in RNA editing levels.
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These processes give rise to a complicated landscape of genomic alterations within an individual tumor and great diversity of these CNAs across tumor samples, making it difficult to identify driver mutations associated with cancer progression.
An important distinction to be made is the difference between a recurrent alteration within a patient population (for example, BRAF V600E in melanoma), and a gene acting as a driver within a particular tumour under a specific context (for example, germline variants, tissue type and therapeutic regimen).
Our results indicate that IC has potential for quantifying the effects of mechanical comminution and hydrothermal alteration within a fault zone.
Here, we consider a Pacific salmon population that may have experienced life-history evolution, in response to habitat alteration, within a few generations.
The initial finding suggests that the proposed method may be engineered into a promising tool for evaluating and monitoring tissue microcirculation and its alteration within a wide-range of cavity tissues in the patients with various pathological conditions.
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