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Finally, I compared the expression level of the target of each driver TF in the tumor samples bearing driver alterations with that of the samples where it was unaltered.
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The cochlear nucleus (CN) is vulnerable to physio-pathological alterations with age that may contribute to varied degree of hearing impairment.
These climate phenomena may act in tandem with or in opposition to human-induced alterations, with consequences that are difficult to predict (Philip and van Oldenborgh 2006; Table 1).
Few will quarrel with the alterations or with that part of the novel Austen writes, which goes on quite heartily, well into Chapter 12, setting up what looks like a knockabout comic novel, a seaside romp.
Since these chosen depictions are almost iconic, quoting from them with alterations that are explicitly construed as political, generates a double-take and immediate scrutiny from the viewer.
CDDP resistance can develop along with alterations that reduce the amount of aquated CDDP forms in the cytoplasm.
Although the DNA sequence alterations found do not have any effect on protein structure and/or function, it is necessary to emphasize that the alterations with amino acid change that were found in the tyrosine kinase domain could be important, because they can affect autophosphorylation (activation) and consequent cellular effect (signalling), allowing constitutive activation of the receptor.
Wood smoke (WS) exposure causes COPD with respiratory alterations that are similar to those described for COPD associated with tobacco smoke (TS).
Glyco-Mapper accurately predicts glycoforms associated with genetic alterations that result in the appearance or disappearance of one or more glycans with an accuracy, sensitivity, and specificity of 96%, 85%, and 97%, respectively, for publications between 1999 and 2014.
The majority of PAX3-High tumors also contain TP53 alterations and the H3.3-K27M H3.3-K27M genetic alterations that also coexist with Pax3 expression in our mutationdel.
Genes transcriptionally upregulated through promoter hypomethylation during malignant progression to high-grade glioblastoma were enriched in cell cycle function, evolving in parallel with genetic alterations that deregulate the G1/S cell cycle checkpoint.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com