Sentence examples for alterations we used from inspiring English sources

In order to confirm that mRNA alterations translated into protein alterations, we used cytoimmunofluorescence to determine the production of fibronectin protein in leiomyoma and myometrial cells in culture.

To dissect the heterogeneity of ovarian cancer and identify histotype-specific alterations, we used an in silico hypothesis-driven approach on multiple datasets of epithelial ovarian cancer.

When cases were subdivided into groups according to genetic alterations, we used polytomous logistic regression, comparing each group of cases with the whole set of controls.

To understand the role of autophagy in age-related NMJ alterations, we used the inducible muscle-specific Atg7 knockout mice that we have recently generated (Masiero et al., 2009).

In order to determine whether the accumulation of alterations observed in our progression model was also accompanied by additional epigenetic alterations, we used methylation-specific PCR (MSP) to determine whether genes that are commonly epigenetically silenced in breast cancer, were also silenced in our cell model.

For copy number alterations we used mean KS segments with ratio ≥1.4 and ≤0.8, and for structural variants we used sites that were validated by de novo assembly and confirmed to be absent from the D lines by alignment-based genotyping (see SV section above).

Since cell lines may contain tissue culture related genomic alterations, we only used primary NB tumor samples for this analysis.

To study epigenetic alterations in FTLD we used lymphoblast cell lines (LCLs) derived from neurologically healthy subjects and FTLD patients.

To verify the link between Shh/Smo signaling and the phenotypic alterations in GBCs, we used cyclopamine, an inhibitor of Smo.

To determine the function of the proteins encoded by genes showing scrapie-associated alterations in expression, we used published literature, the National Center for Biotechnology Information (NCBI), and the Source (Diehn et al 2003).

To investigate motor representation alterations, we will use transcranial magnetic stimulation in combination with a visually guided technique.