Sentence examples for alterations we performed from inspiring English sources

To understand the role of cytoskeleton in nanoarchitectural alterations, we performed selective drug treatment on the specific cytoskeletal components of these cell types and studied the effects of cytoskeletal organization on disorder strength differences.

To evaluate whether selected dysregulated microRNAs in ULMs associated with specific genomic alterations, we performed comparative genomic hybridization (CGH).

Since Arsenate was the best activator of the hsp22 pathway in our assay, and also triggered significant morphological alterations, we performed a finer description of arsenate insult on cell behavior in High Content Analysis.

To further assess whether depletion of Ku70/80 in ALT cells induces gross chromosome alterations, we performed FISH analysis of metaphase spreads using a telomere-PNA probe.

To gain a broader perspective on the results of our analysis of chromosomal CN alterations, we performed a meta-analysis of previously published CN studies.

To search for ultrastructural alterations, we performed electron microscopy (EM) analyses of wild-type, Sgce-null, Sgca-null and Sgca-; Sgce-null mice on skeletal and cardiac muscle at 7 months of age.

In order to validate the protein level alteration we performed the semi-quantitative RT-PCR as a standard method to evaluate the transcription level of these proteins [ 13].

This may be attributable to differences in the technologies used to detect copy-number alterations; whereas we performed aCGH that was specialized for comprehensive and sensitive genomic analysis, Bollati et al. used fluorescence in situ hybridization to detect specific chromosomal aberrations.

To investigate structural and numerical chromosomal alterations we have performed conventional karyotyping of cultured MSC using GTG banding at 300 to 400 band level.

Thus since the enhanced expression of pre-pro-C3 in VSMCs from SHR might be associated with genetic alterations, we therefore performed the direct sequencing of PCR products for promoter lesions of pre-pro-C3 in genomic DNA extracted from liver of SHR and WKY rats.

To correlate the biochemical changes of the PSD regions with morphological alterations at synapses, we performed ultrastructural analysis of dendritic spines in the stratum radiatum of the hippocampus.