Sentence examples for alterations we have from inspiring English sources

The proinflammatory alterations we have found in the phenotype of monocytes from acute Charcot patients appear to be specific to this condition.

To investigate structural and numerical chromosomal alterations we have performed conventional karyotyping of cultured MSC using GTG banding at 300 to 400 band level.

It will clearly be important to test this hypothesis by asking whether the sequence alterations we have identified result in aberrant function in vitro.

It will be critical to examine prospectively whether the alterations we have observed are linked to immunological consequences later in childhood as well as to validate our findings in additional cohorts.

Given that NRF2 inhibitory complex alterations are known to drive NRF2 pathway activation, we speculate that the alterations we have identified may contribute to the high frequency of aberrant NRF2 activation reported in ovarian cancer [ 18].

One of the main limitations of this study is the lack of protein level and/or localization analysis of complex components and NRF2 in OVCA tissues to confirm the biological effects of the DNA and mRNA level alterations we have described.

One of the biggest alterations we've experienced in recent years is the use of content recommendation networks.

In order to constrain the nature and extent of the aqueous and thermal alteration, we have investigated the bulk mineralogy and abundance of H2O in the CI and CI-like chondrites using thermogravimetric analysis and infrared spectroscopy.

Interestingly, the alterations that we have found in the neocortex and hippocampus of LMH pups are in concordance with such studies.

If we can identify how these risk factors impact on breast development and in particular understand the molecular changes within breast epithelium that lead to genomic alterations, then we have a chance to establish preventative strategies to ameliorate the disease.

Of the seven (18.4%) MSH6 alterations found, we have identified three novel germline mutations, one 8 bp deletion leading to a truncated protein and two missense mutations resulting in the substitution of amino acids belonging to different polarity groups.