The phrase "alterations using a" is correct and usable in written English.
It can be used when discussing modifications or changes that are made with the help of a specific tool, method, or material.
Example: "The alterations using a new software program have significantly improved our workflow."
Alternatives: "modifications with a" or "changes utilizing a".
In light of urban and agricultural development, our ability to detect responses of exotic species to landscape alterations using a combination of simple physical and land cover variables exemplifies a cost-effective technique for assessing areas at greater invasion risk in large stream systems.
The data was smoothed using a three-clone sliding window and CGH plotter [29] was used to identify the extent of alterations using a segmentation constant of 7. Log2 ratios for two continuous BAC clones outside the threshold ranges were classified as copy number changes including gain (threshold +0.25), loss (−0.25), amplification (+1) and homozygous loss (−1).
We also identified genetic alterations using a primer corresponding to a topoisomerase II binding site consensus.
Our study has three principal aims: 1) Detection and high resolution mapping of amplicons in NB. 2) Detection of low copy number genomic alterations using a probabilistic approach.
In this pilot study, we have searched for the genetic alterations, using a total of 109 microsatellite markers representing 24 chromosomal regions, in the serum DNA of patients with primary liver cancer, i.e. HCC (n=21) and CC (n=6).
The ten BLBC specimens were assayed for genetic alterations using a whole-genome tiling path bacterial artificial chromosome (BAC) array in comparative genomic hybridization (CGH) experiments as previously described [ 12].
We compared the expression profiles of cells exposed to these various particles before and after alteration, using a low concentration (20 μg/mL) about eight times lower than that producing the first visible loss of viability by XTT test.
Thus, we hypothesized that DNA methylation profiling either by itself or combined with genetic alterations using aCGH therefore might be a useful tool to distinguish between de novo and recurrent tumours.
We interrogated diet-induced epigenomic, transcriptomic, proteomic, and metabolomic alterations using high-throughput omic methods and used a network modeling approach to integrate these diverse molecular signals.
In this paper, we present a new approach named CNVplex® for the detection of chromosomal alterations using CNVs in the 22q11.2 region as a test model.
As MTHFS has 2 different transcripts (A: ENST00000258874, protein coding; and B: ENST0000050919, putative nonsense mediated decay), a semi-quantitative analysis was done to determine whether the methylation alteration resulted in isoform-specific alterations, using RIMBP2 [MIM 611602] as a control gene considering its uniform expression in heart.
