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Calle and Urrea found that MDA was unstable when there were small alterations to the data, but that MDG was robust to such changes [ 36].
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We did not make substantial alterations to the original data.
The design of the application ensured that users would not be able to use their phone to make alterations to the logged data.
Data management will be undertaken using a Microsoft Access database for data entry and processing, allowing a full audit trail of any alterations made to the data postentry.
A clinical data management software package will be used for data entry and processing, allowing a full-audit trail of any alterations made to the data post entry.
Most of the previous studies which have correlated p16 alterations to survival data are limited by the fact that a comprehensive analysis of the p16 genetic alterations is lacking.
Obviously, this reduces the precision of the original point clouds; however, the results obtained for different objects (Figure 10) from the Stuttgart University Database [32] demonstrate the algorithm is robust to these alterations of the data.
To test our reasoning we applied popLowess to data set 7. Samples in this set have little to no genomic alterations but the data display variation in M-A curvature and spatial effects.
Quantitative robustness concerns the degree to which the summary effect size from meta-analysis tends to change based on relatively small alterations in the data.
9– 11 For assessment of the ability of the CGA to detect previously unrecognized health problems, the studies had to contain information on the frequencies of CGA domain alterations or on the data needed to compute these frequencies.
Qualitative robustness refers to whether the evidence base yields the same qualitative general conclusion upon alterations of the data.
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