Studies in developmental toxicity have shown that subtle developmental alterations are easier to detect when subjects confront challenging or stressful situations (Cory-Slechta 1990; Rice and Baron 2000).
Assessment of respiratory function is the principal tool in the study of patients with lung diseases, allowing physiopathological alterations to be detected, and the severity of the process, its clinical course, and treatment response to be identified.
Note that there may be even more dysregulated regions with methylation alteration too small to detect above noise in these samples.> -wrap-foot> Columns are as in Table 3.
However, BACs, which are usually 100 200 kb, may miss alterations smaller than the size of a clone but are less likely to detect alterations of unclear clinical significance.
In practice, the distribution and length of the spotted array elements determine the detection sensitivity to various alteration sizes with some recent platforms being able to detect alteration sizes less that 100-kb [ 2].
The phenomenon that Dr. Wolfe's Pop Art quiz exemplified is known as change blindness: the frequent inability of our visual system to detect alterations to something staring us straight in the face.
Numerous neuroimaging studies have used functional connectivity analysis to detect alterations in brain function in migraineurs and have revealed that neuroimaging alterations correlate with longer migraine duration and increased migraine frequency [4 8].
With a grant from the Federal Bureau of Investigation, which is interested in ways of authenticating digital images presented in court, Dr. Farid is devising algorithms to detect alterations.
Moreover, we estimated the effect size of the differences in the executive performance between polysubstance users and non substance users in order to know which neuropsychological tasks can be useful to detect alterations in the executive functions.
This review concludes by discussing problems occurring during electrospray that can adversely affect the functional properties of biomolecules, along with techniques to detect alterations in their properties and recommendations to prevent such changes.
