The phrase "alterations that reduce" is correct and usable in written English.
It can be used when discussing changes or modifications that lead to a decrease in size, quantity, quality, or intensity of something.
Example: "The report highlights several alterations that reduce the overall cost of production."
Alternatives: "changes that lessen" or "modifications that diminish".
This fishery is affected not only by habitat alterations that reduce clam stocks, such as beach erosion, but also by the risks to humans consuming clams from polluted areas.
Deficiencies in DNA repair enzymes are occasionally caused by a newly arising somatic mutation in a DNA repair gene, but are much more frequently caused by epigenetic alterations that reduce or silence expression of DNA repair genes.
If the nuclear shield is a functionally important structure, as proposed here, genetic alterations that reduce its thickness or modify its enzyme composition should affect the protective role and possibly result in pathological phenotypes.
These data indicate that MR induces gene expression alterations that reduce hepatic lipid storage and promote fatty acid oxidation.
CDDP resistance can develop along with alterations that reduce the amount of aquated CDDP forms in the cytoplasm.
Published evidence suggests LIMD1 is silenced through genetic alterations that reduce expression levels rather than mutations to coding regions that affect activity [5].
Factors not amenable to alteration that reduced the likelihood of an uncomplicated pregnancy were being in a lower fifth of socioeconomic index, the presence of hypertension before pregnancy while using oral contraceptive pills, family history of any hypertensive disorder in pregnancy, and vaginal bleeding during pregnancy.
Many modifications are deleterious to protein function because of alterations in protein folding that reduce or eliminate functional activity (e.g. enzyme activity).
The impact of alterations in penicillin-binding protein that reduce penicillin susceptibility have less effect on the activity of third-generation cephalosporins such as ceftriaxone with 3.4% and cefotaxime with 4.6% resistance, respectively.
Homology modeling using the Escherichia coli enzyme structure suggests that the replacement of the critical nucleophile OH− in the Thr84 residue of the wildtype of MtFBPase by Ser84 results in subtle alterations of the position and orientation that reduce the catalytic efficiency.
Mutations that reduce the activity of IIS can increase lifespan in all three organisms, often in conjunction with associated alterations in growth, stress resistance, metabolic phenotypes and fecundity.
