Sentence examples for alterations that modify from inspiring English sources

Tumor development occurs when a cell accumulates genetic alterations that modify normal cell cycle progression.

Posttranslational modifications, such as citrullination, methylation or glycosylation, are common alterations that modify protein structure and possibly stability, functionality and antigenicity of proteins.

Additionally, in recent years, it has been reported that many miRNAs go through post-transcriptional alterations that modify their 3′ end, mainly via mono/poly-Uridylation (Heo et al., 2009, 2012) or poly-Adenylation (Shanfa et al., 2009).

Such genetic effects are expected to be mediated in large part via conditionally adaptive responses to environmental variation, which involve epigenetic alterations that modify gene expression and developmental phenotypes (e.g. Bruce and Hanson 2010).

The lack of evidence on the best pattern of iron supplementation could correspond to other factors, apart from the dietary intake of iron, such as iron status of the woman during the first trimester [ 6, 16- 18], or the presence of a genetic alteration that modifies the intestinal absorption of iron.

The effect of electromagnetic radiation on biological objects extends from heating to complex photochemistry, and includes DNA alteration, that properly modified in damaged cells may entail beneficial effects.

Another explanation is that our model, which represents wild-type strains, disregards the alterations that occur in modified organisms due to the production of recombinant protein.

Although we did not assess electrical conduction in the present study, exposures to O3, PM2.5, or O3 + PM2.5 may initiate ECG alterations that were further modified in HFrD rats to decrease heart rate.

If the nuclear shield is a functionally important structure, as proposed here, genetic alterations that reduce its thickness or modify its enzyme composition should affect the protective role and possibly result in pathological phenotypes.

It may be critical to examine the potential to intervene in pathways understood at the molecular level to improve appetite, modify metabolic alterations that contribute to wasting, and downregulate transcription factors or cytokine-induced events to treat CC.

The mineralogical properties of aggregate interplanetary dust particles (IDPs) and matrix of CI and CM carbonaceous chondrites support a sequence of increasingly intense aqueous alteration that could have modified pristine organics in aggregate IDPs to more complex organic compounds in chondrite matrix.