The phrase "alterations that increase" is correct and usable in written English.
It can be used when discussing changes or modifications that lead to an increase in a particular aspect or quality.
Example: "The alterations that increase efficiency in the production process have been implemented successfully."
Alternatives: "changes that enhance" or "modifications that boost".
This leads to subsequent cellular alterations that increase the risk of cells altered by pre-cancerous genetic changes [ 3, 23- 28].
Scientists have since come up with single-gene alterations that increase the life spans of Drosophila fruit flies, mice, and yeast.
A study led by Yufeng Shen suggests that cancer data could be used to pinpoint rare, damaging genetic alterations that increase the risk of developmental syndromes like autism.
Critical illness is hallmarked by insulin resistance and mitochondrial damage, metabolic alterations that increase circulating levels of FGF21 via the integrated stress response (ISR) [2].
Noto et al. [21] recently demonstrated that patients with a history of KD have long-term structural and functional alterations that increase the propensity towards subclinical atherosclerosis with age.
It plans to cull these variations to find patterns of particular mutations that predispose patients to major killers such as heart failure, as well as genetic alterations that increase the risk of side effects from prescription drugs.
As a reciprocal test of this premise, Rizki and Lundblad (2001) examined the consequences of genetic alterations that increased the frequency of genetic exchanges between telomeric repeat DNA.
Taken together these data indicate that the Rad as well as Rad + Csc treated cells acquired genetic/biochemical alterations that increased the cells ability to migrate and invade, i.e., a possible increase in dissemination or metastatic potential.
At each step of the optimization procedure, every possible edge or position addition, removal or edge reversal that produces a valid, acyclic network is evaluated, and the alteration that increases the score ℓ′ the most is kept.
In another study, a 857 T polymorphism in tumor necrosis factor α (TNF-α), which is a potent immuno-modulator and pro-inflammatory cytokine, has been shown to be associated with ATLL patients compared to healthy subjects, suggesting that the genetic alteration that increases the production of TNF-α is associated with a susceptibility to ATLL [ 13].
Furthermore, sequencing of the active CIP2A promoter region from altogether seven normal and malignant cell types did not reveal any sequence alterations that would increase CIP2A expression specifically in cancer cells.
