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If one thing is changed, there might be a whole series of other alterations that cause things to remain as they actually were.
It is now believed that the cellular and molecular alterations that cause brain dysfunctions are slow in onset and that it probably takes several years to develop the full blown disease [1].
Indeed, cancer is a complex disease characterized by the accumulation of several and often unknown molecular alterations that cause genetic instability, cell proliferation, and acquisition of an increasingly invasive phenotype resistant to therapeutic treatments.
Impaired Swi6 function leads to mitotic alterations that cause severe growth alterations.
Therefore we used genome wide screens to identify genetic alterations that cause resistance in our model.
Given that hearing loss in early childhood can affect linguistic development [ 16], it is important to improve current techniques for identifying genetic alterations that cause NSHL.
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Reactive oxygen species (ROS) trigger a biomolecular alteration that causes functional and structural changes.
Moreover, the abrupt increase in IC value accompanied by high illite peak intensity (Figure 5a) is explained by hydrothermal alteration that causes plagioclase breakdown and formation of white micas (Figure 6e,f,g).
At the spot where the laser is focused, the light kicks off a chemical alteration that causes the spot to fluoresce the next time it's exposed to the light.
The ACMG category (1) and the IARC 'pathogenic' classification both refer to a deleterious mutation, a genetic variation or sequence alteration that causes an elevated risk of disease.
The majority of analysed samples exhibited one specific B-Raf alteration that caused the exchange of valine to glutamate, a negatively charged amino acid, at position 599 (V599E) in the kinase domain of the protein.
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CEO of Professional Science Editing for Scientists @ prosciediting.com