Sentence examples for alterations specific to from inspiring English sources

Based upon patient-specific aberrations in pathways or known markers, both existing and new therapies can be tailored to benefit patients based on the risk of progression and molecular alterations specific to a patient's tumor.

The more frequent expression of COX-2 in LSCRCs as compared with RSCCs supports the hypothesis that COX-2 expression may be related to genetic alterations specific to rightor left-sided CRCs.

Since then, overall plasma DNA concentration in cancer patients and genetic or epigenetic alterations specific to tumor DNA have been investigated in patients diagnosed with different types of cancer.

Different from that, proteins that were altered only in a single cell line are called here "cell line-specific proteins" to denote protein alterations specific to a cell line characterized by a distinct genetic alteration (114 proteins, see above).

This result, although surprising, does not preclude the possibility of alterations specific to particular cellular regions.

Further studies are necessary to shed more light on the neuroradiological alterations specific to dysexecutive MCI.

The frequency plots and a detailed description of the recurrent regions of alteration specific to these SCLC and NSCLC cell lines have been reported (Coe et al, 2006; Garnis et al, 2006).

Specificities are observed for some alterations and anatomical subtypes: frequent fibroblast growth factor receptor 2 (FGFR2) and isocitrate dehydrogenase 1/2 (IDH1/2) alterations are specific to intrahepatic cholangiocarcinomas (ICCs), whereas frequent ERBB2 oncogene alterations are specific to extrahepatic cholangiocarcinomas (ECCs) and gallbladder carcinomas (GBCs).

Notably, the nucleolar proteome is significantly altered under stress conditions and the alterations are specific to particular forms of stress [ 59, 60].

Future studies are needed to determine whether the scrapie-associated alterations identified in mice also occur in other animals and humans with TSEs, and whether the alterations are specific to prion disease.

In order to assess whether potential APP-induced alterations were specific to LDLR, we immunostained for LDLR and another member of the LDLR family, LRP (LDLR-related protein-1) (Figure 2A).