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By modulating these pathways, BAG3 appears to mediate cell adaptive responses to stressful stimuli, and its alterations result in altered homeostasis and reduced cytoprotection, explaining why its expression is often found deregulated in a vast series of tumors.
The speciation process may also be initiated by changes in just one or a few gene loci when these alterations result in a change of ecological niche or, in the case of parasites, a change of host.
When genetic alterations result in growth factor-independent c-Myc expression, it can become an oncogene.
The LEIS technique allows detecting the precision alterations result from corrosion process, which can not be found by optical image.
Surface proteins are probably the most Ag+-sensitive sites, and their alterations result in bacterial disruption due to structural and severe metabolic damage.
These alterations result in significant shortening of the spine and of the fetus due to marked lordosis with hyperextension of the head.
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This combination of alterations results in a markedly altered current profile under AP voltage clamp (Fig. 5).
It is the molecular alterations resulting from these ionizations and, in turn, the resultant biochemical changes that give rise to various types of injury.
The physical complex includes buildings, transportation networks, modified surfaces (e.g., parking lots, roofs, and landscaping), and the environmental alterations resulting from human decision making.
Microstructural alterations resulting from exposure to chlorides and carbon dioxide are discussed.
The alterations resulting from this surface modification on the fatigue crack growth of FSW were characterized and evaluated for two different crack configurations.
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