The phrase "alterations required to" is correct and usable in written English.
It can be used when discussing necessary changes or modifications that need to be made to something.
Example: "The alterations required to the project plan will ensure that we meet the new deadlines."
Alternatives: "changes needed for" or "modifications necessary to".
The Real Estate Board of New York raised the specter of a regulatory regime that would make it difficult for owners of even the most undistinguished buildings in the district to make alterations required to attract or keep tenants.
These findings suggest that accumulation of MYC protein is sufficient to transform prostate luminal epithelial cells into PIN cells in vivo without a concomitant need for additional alterations required to suppress apoptosis.
The astounding process known as uridine insertion/deletion RNA editing produces the dramatic alterations required to convert skeletal primary transcripts into functional messages through the post-transcriptional addition of up to half of the coding information.
In such a scenario, the limited number of additional alterations identified in UCa would suggest this to be a "default" pathway in bladder carcinogenesis, with significant additional alterations required to develop the squamous phenotype.
Myriad genetic and epigenetic alterations are required to drive normal cells toward malignant transformation.
Furthermore, although no fundamental alterations were required to the amount of reinforcement, the cross-section's height was increased to maintain the maximum deflection within the limitations imposed by EC2.
These were calculated for a previous study, however a couple of alterations were required to get a consistent behaviour, specifically positive and negative values relating to synergy and antagonism respectively: pBeta and pGamma were derived from Beta and Gamma [25] by taking the negative based-10 logarithm.
As it turned out, J. Lo did a pretty damn good job in capturing the spirit and vocal style of Selena, and no physical alterations were required to achieve authenticity.
It is presumed that other genetic alterations are required to initiate invasive UCC.
Finally, it appears that in addition to TP53 variations, the presence of additional genetic alterations are required to predict the individual risk for radiation-induced secondary cancers [ 45, 46].
