The phrase "alterations point" is not standard in written English and may cause confusion.
It could be used in a specific context related to changes or modifications, but it is not commonly recognized.
Example: "Please refer to the alterations point in the document for the latest updates."
Alternatives: "modification section" or "change reference".
These behavioral alterations point to defects beyond the locomotion system and may reflect a more global function of CHN-1, as expected for a CHIP homolog in a higher eukaryote32.
Some of these alterations point towards a peroxisomal dysfunction.
Indeed, some of the observed mRNA alterations point out changes characteristic for oxygen deprivation.
All these molecular alterations point toward a possible implication of Twist1.
We then analyzed the association between recurrent somatic alterations (point mutations and SCNAs) and number of rearrangements.
Also, genome-scale approaches to study the epigenetic alterations point out a possible association of global hypomethylation and different neurological disorders as schizophrenia or bipolar disorder [ 8, 9].
It is interesting to note that other brain areas of PILOnoSE rats do not show any significant T2-w alterations, pointing out a crucial role of the thalamus.
In general, the results reviewed here for the fate of Aβ and apoE after SVD-related BBB alteration point to two different effects of protein retention in the brain (1) accumulation, as documented for Aβ, and (2) degradation as presumed for apoE.
These changes, however, were not associated with alterations in point-for-point matching measures of estradiol.
Recently, BoydLk et al. [ 32] pointed out that prostate cancer is a genetic disease characterized by multiple genomic alterations, including point mutations, microsatellite variations, and chromosomal alterations such as translocations, insertions, duplications, and deletions.
Large-scale genomic studies have identified multiple somatic aberrations in breast cancer, including copy number alterations and point mutations.
