Sentence examples for alterations play a from inspiring English sources

Recently it became apparent that not only genetic but also epigenetic alterations play a major role in carcinogenesis.

Introduction: Chloride alterations play a major physiologic role in the development of acid base disorders.

While it seems clear that serotonergic alterations play a role in the pathogenesis of these major public health problems, dysfunction in additional neurotransmitter systems and other molecular alterations may also be implicated.

Of particular importance are the MAPK and PI3K/Akt pathways, which, through their genetic alterations, play a critical role in the development and pathogenesis of melanoma and are therefore tested vigorously as important therapeutic targets for this cancer [6], [10] [15].

Microcirculatory alterations play a pivotal role in sepsis and persist despite correction of systemic hemodynamic parameters.

Clearly, genetic alterations play a role in pancreatic fibrosis of this rat strain.

Its alterations play an important role in tumorigenesis and tumor-suppression.

Several important physiological functions require the cooperation of microbiota/microbiome, whose alterations play an important role in several human diseases.

While many of the key mechanisms underlying its carcinogenic effects remain unknown, there is increasing evidence that chromosomal alterations play an important role in the development of the induced leukemias.

Epigenetic alterations play an important role in the molecular pathology of GBM.

Microvascular alterations play an important role in development of organ failure [ 1].