The phrase "alterations participated" is not correct and does not convey a clear meaning in written English.
It seems to be an attempt to describe involvement in changes or modifications, but it lacks clarity and proper grammatical structure.
Example: "The team members were involved in the alterations participated during the project."
Alternatives: "changes made" or "modifications involved".
We and other groups have revealed that DNA methylation alterations participate in renal carcinogenesis and are significantly correlated with the clinicopathological diversity of ccRCCs [ 7– 11].
In fact, ROS production was implicated in DNA damage observed in U87-MG and U251-MG cells, but not in LN229, indicating that other molecular alterations may participate, such as alteration of the DNA-repair machinery, the acetylation of histones involved in DNA repair such as Histone 4 or histone 3 and the decrease in G2 checkpoint kinases.
If one hypothesizes that persisting long-term immune alterations may participate in increased risk for additional infections in septic patients, the present results are somehow unexpected.
Those alterations probably participate in cascades of pathogenic events, which eventually cause clinical symptoms.
Furthermore, mutations in SCRIB SADH domains associated with spina bifida and cancer impact the stability of SCRIB at the plasma membrane, suggesting that SADH domain alterations may participate in human pathology.
We reasoned that a similar approach might help us to identify epigenetic alterations that participate in the acute effects of METH on gene expression in the rat dorsal striatum of METH-naïve and METH-pretreated rats.
In our series, the increased activity of ERK1/2 proteins was mainly a consequence of a combination of mutations in upstream NRAS/ BRAF components of the pathway and silencing of the p16 CDKN 2 A gene (although additional - and yet unidentified - functional alterations may participate in inducing such a ERK activation) (see Figure 1).
Surprisingly, we found that glucose uptake and metabolization is altered after oncogenic stress and this alteration participates in senescence.
In addition to copy number alterations, genome-wide DNA methylation alterations may also participate in the development of UCs belonging to cluster B2.
Their alterations indicated that autophagy participated lipid metabolism to generate energy and form autophagosomes with significantly increased free fatty acids and glycerophospholipids, which protected wild-type MEFs from serious damages and delayed cell death.
