Sentence examples for alterations of the activity from inspiring English sources
The respective NSAIDs might interfere directly with the transcription factors, but their effects are probably mediated predominantly through alterations of the activity of cellular kinases such as IKKβ, Erk, p38, or mitogen-activated protein kinase [ 51].
Studies from Kobayashi et al showed that alterations of the activity of the rho family small GTPases leads to changes in actin filament assembly and in foot process formation [45].
Damage by these microbes was demonstrated by alterations of the activity of a constitutively expressed luciferase in the host, as well as by using fluorescent probes indicative of altered host cell permeability.
In particular, a significant increase of cytokines and growth factors in peritoneal fluid, some alterations of the activity of B lymphocytes, increased antibody response, and an increase of concentration and activity of peritoneal macrophages have been observed [ 72, 73].
Therefore, we checked whether the identity changes observed during the reconstruction of compartment boundaries are associated with alterations of the activity of the Pc-G and the trx-G genes.
While we only found modest changes of selected markers of these cytokines and metabolites in our pilot study of ADHD [ 11], we hypothesized here that key symptoms and poor attentional function would reflect alterations of the activity of these markers.
Interesting recent developments include the development of protocols which enable us to monitor protection towards genotoxic chemicals contained in the human diet, and it was shown in preliminary studies that alterations of the activities of drug metabolising enzymes by dietary factors lead to altered sensitivity of lymphocytes against DNA damage caused by certain dietary carcinogens.
The highly regular geometry of the compound eye makes this a very sensitive system to study the effect of slight alterations of the activities of genes involved in its development.
High degree nodes are the most relevant ones in interactome networks, as they represent the fulcrum of multiple signaling pathways, and their positive/negative modulation could result in alterations of the activities of their likely interactors.
Chemicals of herbal products may cause unexpected toxicity or adverse effect by the potential for alteration of the activity of CYP450 when co-administered with other drugs.
The impaired metabolism is often accompanied with excessive release of free radicals through lipid peroxidation, due to alteration of the activity of several proteins [ 2], aggravated by a drastic drop in antioxidant immune mechanisms [ 3].
