The phrase "alterations of stem" is correct and usable in written English.
It can be used in contexts related to biology, linguistics, or any field discussing changes or modifications to a stem structure or concept.
Example: "The alterations of stem in this plant species are crucial for its adaptation to the environment."
Alternatives: "modifications of stem" or "changes to stem".
Knowledge gained from these studies portends the alteration of stem cell fate in the absence of biological factors, which would be valuable in the engineering of complex organs comprising multiple cell types.
To examine whether this alteration of CD24 expression in the colon of DBZ-treated mice was paralleled by an alteration of stem cell activity, we studied Lgr5 mRNA levels in the isolated fractions of colonic crypts.
The difference in the relative frequency of CD44+/CD24- and ALDH1+ cells between basal-like and HER2+ tumor subtypes may reflect their distinct cell-of-origin or the alteration of stem cell-like gene expression programs due to tumor subtype-specific transforming events [ 39].
Alterations of the stem design like the so called anatomically adapted stems which are designed for a proximal force transmission are not able to reduce the proximal bone resorption significantly, as shown by Venesmaa et al. [ 19].
In vivo, we expect autocrine feedbacks to be highly sensitive to alterations of the stem cell microenvironment, hence our model can guide future studies linking stem cell maintenance to physical and biochemical properties of the stem cell niche.
Nevertheless, strong evidence suggests that most tumours originate from CSCs through neoplastic alterations of adult stem or progenitor cells [ 2, 9, 59].
This evidence indicates a role for Pin1 in determining self-renewal and replicative potential of mammary stem cells thus implying alterations of the mammary stem cell compartment in Pin1 −/− mice.
GL26 analysis confirmed immune alterations, specific acquisition of stem cell markers, specifically enhanced sensitivity to anti-stem drug (cyclopamine), and enhanced tumorigenicity in wild-type hosts, in tumors in proportion to anti-tumor T cell activity.
The molecular characterization of adult ETP-ALL revealed distinct alterations with overexpression of stem cell-related genes (BAALC, IGFBP7, MN1, WT1).
Furthermore, virtually all stem cells imaging technologies require some degree of ex vivo alteration of the stem cells prior to implantation of the cells, and so efficiency of alteration is also a requirement.
