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Our data indicate that epigenetic alterations of relevant genes are present in developing heart DNA in fetuses with both isolated and syndromic heart malformations.
We describe the cell line in terms of growth characteristics, phenotype, and genotype for their unique DNA and RNA profile using Affymetrix microarray technology as well as for specific alterations of relevant tumor-associated genes.
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Alterations of function relevant to neuronal support could be masked by other sources of S100B production.
Furthermore, markers of genetic alterations may permit the detection of relevant early stages of malignancy to inform surveillance and effective treatment, and provide an approach to disease classification.
However, the atomic structures of defects, interfaces, and surfaces are all preferentially affected by beam-induced object alterations because the binding energies of relevant atoms are significantly lowered compared to those of bulk lattice sites in crystalline solids.
The aim of this study was to clarify relevant alterations of gene expression associated with the invasive phenotype of oral cancer.
Our data also indicate relevant alterations of acylcarnitines (AcCs) and amino acids (AA) profiles in BCSCs.
Other relevant alterations of miRNAs in CLL include downregulation of miR-181a, let-7a, miR-30d, miR-150 and miR-92 [ 29] and overexpression of miR-155.
The aim of this study was to clarify relevant alterations of gene expression associated with the early stage of colorectal carcinogenesis.
Thus, compared with the other approaches, the reference-free method may demonstrate superiority in identifying biologically relevant alterations of DNA methylation in highly heterogeneous tumor samples.
To clarify relevant alterations of gene expression associated with early colorectal carcinogenesis, we analysed the gene expression profiles of tumour tissues by a cDNA array (Yamamoto et al, 2002).
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