Sentence examples for alterations of potential from inspiring English sources

The application of new genomics and proteomics techniques to our model, with its gradual stepwise development of pathological lesions, could be useful in identifying sequences of alterations of potential relevance to human prostate cancer, and in particular, cancers featuring the loss of PTEN.

On the other hand, rare germline alterations of potential disease genes have not been investigated for the most common non-familial (sporadic) form of breast cancer, which accounts for the majority (70 to 80%) of all breast cancers in the population.

In the current study, we pursued an exome-sequencing strategy using DNA isolated from (clonal/tumor) eosinophils that were purified to near-homogeneity from a patient with KITD816V-mutated ASM with associated eosinophilia, in order to identify genetic alterations of potential pathogenetic significance.

This study examines the alteration of potential hydrodynamics due to wind-induced trim (geometric non-linearity) and its impact on the wind turbine׳s wave response with focus on heave plate performance.

Similar alterations of resting potential were reported in neocortical cells/dentate granule cells of APP/PS1 mice model of AD [15] and in vitro Aβ application was known to depolarize neuron [76], [77], suggesting a key role of Aβ pathology in alteration of resting potential.

The hydrogen effect is attributed to the alteration of chemical potential and exchange current density of steel.

We ascribe a dramatic alteration of the potential curves with the increase of the separation between QDs from 5 to 20 nm observed in Figure 2 to the interplay between the structural confinement and the electron-electron repulsion.

G46V involves no alteration of electrostatic potential or H-bonding or induction of steric clash.

The alteration of redox potential of the membrane by CYSTM proteins might also affect the uptake of certain compounds and also allow quenching of potentially damaging radicals.

It is noteworthy that the phenomenon of impaired membrane trafficking due to alteration of electrostatic potential was previously reported in case of an opsin mutation as well [ 37].

Extensive study based on animal model may contribute to understanding the exact mechanism of action and toxicity level/side effect without alteration of therapeutic potential.