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Diffusion weighted imaging studies have shown alterations of large white matter tracts, most notably in left temporal lobe epilepsy, but the degree of altered connections between cortical and subcortical structures remains to be clarified.
We observed that TC-PTP +/− mice were more sensitive to DSS treatment than TC-PTP+/+ mice as shown by histopathological alterations of large bowel, increased cytokine expression in serum and cytokine signaling in the large bowel.
However, even the earliest lesions showed marked alterations of large domains as seen in the later cancers.
Furthermore, we observed some large methylation changes that were specific to one or a few twin pairs (Supplementary Material, Table S5), suggesting that some rare epigenetic alterations of large effect may be associated with psychosis.
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Alterations of larger chromosome segments were found in tolerant cells including losses (5p, 6, 9, 12p and 21q) and gains (5q, 10, 11, 12p, 13q and 18q) in Line2-T500, as well as losses (3p, 7q, 11q, 16q and 17q) and gains (1q, 3q, 4p, 5p, 8q, 11, 17q, 18q and 22q) in Line3-T200 (Table 1).
Human agency also fosters the alteration of large-scale drivers of change at the local level.
The ground floor room to the east of the archway was the College bakehouse where evidence existed prior to the 1845 alterations of a large bakery oven.
In the early 1980s, the architect David Gura oversaw a radical conversion of the Pythian Temple into apartments, a devilishly complicated alteration because of large beams, the windowless facade, and double-height lodge and other rooms.
More alterations and a higher frequency of large alterations (entire chromosome arms deletion or amplification) were found in the EGFR mutated group suggesting that carcinogenesis pathways are different.
Furthermore, in order to identify prognostic alterations, the analysis of large numbers of well documented tumour samples with ample and accurate clinical follow-up data is required.
Stone shattering led to flattening and deep alteration of a large part of the original karstic landscape and to demolition of drystone walls.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com