The phrase "alterations of key" is correct and usable in written English.
It can be used in contexts related to music, discussing changes in the key signature or tonal center of a piece.
Example: "The composer made several alterations of key throughout the symphony to create a more dynamic listening experience."
Alternatives: "changes in key" or "modulations of key".
There was, in other words, the sense of repeating verses but with it subtle and not-so-subtle alterations of key and detail to fit the mood swings of the texts.
This review describes the recent advances in our understanding of the genetics of ALL, with an emphasis on those alterations of key pathogenic or therapeutic importance.
Changes in the thymic stromal compartment and alterations of key signaling pathways in thymocytes result in an aberrant development and the lack of regular T cells.
Alterations of key elements of the apoptotic pathway have been shown to be determinant in the outcome of NBLs.
Therefore, detailed understanding of the alterations of key matrix proteins is essential in deciphering the mechanisms of LV remodelling after MI.
Indeed, maternally or paternally transmitted non-erased epigenetic alterations of key developmental genes may perturb early trophoblast development in a sex-specific manner.
Resistance is often associated with 1) inhibition of alteration of key enzymes that are targets for antimalarial drugs or 2) alteration of drug accumulation into the parasite which results from reduced uptake of the drug, an increased efflux, or a combination of the two processes.
In addition to the fragmentation of mitochondrial morphology noted above, there are many other factors which could contribute to the profound alteration of key aspects of mitochondrial function following their isolation.
Among underlying causes of cancer is accelerated or deregulated proliferation, with alteration of key cell cycle regulators and perturbation of proliferative negative retrocontrols such as cell cycle checkpoints or DNA damage response.
Following on from previous studies within this laboratory (Bartlett et al, 1998, 1999; Watters et al, 2000, 2001) which associated specific chromosomal aberrations with recurrence or progression, we hypothesised that alteration of key cell cycle modulators c- myc and CCND1 via gene alterations drives progression of superficial and locally invasive TCC (pTa/pT1).
Collectively, these data suggest that compromised insulin secretion in Rfx6-deficient β cells is the consequence, at least in large part, of the combined alteration of key steps in glucose signaling due to a failure of Rfx6 to directly promote the expression of key genes.
