The phrase "alterations of interest" is correct and usable in written English.
It can be used in contexts where you are discussing changes or modifications that are significant or relevant to a particular subject or field.
Example: "The report highlighted several alterations of interest that could impact the project's outcome."
Alternatives: "changes of significance" or "modifications of relevance".
However, these genetic alterations are of interest to researchers for several reasons including; the rate of occurrence in NSCLC and/or the ability of these changes in the genome to drive oncogenesis.
Among studies reporting gray matter alterations, of particular interest is the study showing a correlation between the thinning of fronto-parietal areas and the severity of autistic impairment [20].
Water based EOR by wettability alteration is of interest among the oil companies because of economic and environmental reasons.
Early alterations of function are of interest since they may contribute to the development of irreversible pathological events.
To confirm this absence of copy number alterations in our genes of interest and enhance the probability of finding new mutations, we extended our series to a panel of selected patients with recurrent fever (N = 88, Figure 1) with either one MVK punctual mutation for MKD, or urticaria and/or neurosensorial symptoms for CAPS.
Protein changes were determined by label-free LC MS/MS analysis and alterations in proteomic hits of interest were confirmed by comparative immunblotting.
Both transcriptional and genomic profiling were performed on 69 resected NSCLC specimens and results correlated with mutational analyses and clinical data to identify genetic alterations associated with groups of interest.
To further test the clinical relevance of the main identified autism links as diagnostic features of autism, we applied a support vector machine (SVM) approach using the alterations in the regions of interest as a biomarker to test how well this could discriminate patients with autistic spectrum disorder from the healthy controls, that is, classify individuals into one of these groups.
However, with regards to assessing changes in sway or pain intensity at the follow up recordings, sample size calculations are unable to take this into account as the number of patients that did or did not show alterations in the variable of interest cannot be predicted.
Of interest, alterations in both memory capacity and responses to stress also have been observed in mice that lack a molecule called p300/CBP-associated factor (PCAF), which has a similar function to CBP and also has HAT activity (Kalkhoven 2004; Maurice et al. 2008).
