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Mitochondria have been implicated in the process of carcinogenesis, which includes alterations of cellular metabolism and cell death pathways.
Recognition of pathogens by innate and adaptive immune cells instructs rapid alterations of cellular processes to promote effective resolution of infection.
These results indicate that NEFH regulates mitochondrial function, leading to alterations of cellular respiration and glycolysis.
The CMP model demonstrates that at multiple levels of experimental interrogation systemic alterations of cellular function, that may act in concert to allostatically [149] create a multi-dimensional phenotype that could be useful for research into aging and neurodegeneration.
We have attempted to create a viable cell model of long-term, low-level oxidative stress and use this to investigate, at multiple levels, the alterations of cellular function and physiology imposed by this tolerable insult.
Alterations of cellular metabolism play a central role in the development and progression of cancer.
Similar(31)
The introduction of viral particles induces oxidative stress and can alter cellular antioxidant levels; this alteration of cellular protein levels [ 23, 24] may have unexpected redox-related consequences beyond potential off-target silencing, consequences that may substantially alter the redox capacity of the knockdown cells.
Free radicals play vital role in tumor promotion by alteration of cellular metabolic processes and their scavengers (SOD and LPx).
EM studies have expanded our knowledge of viral entry, viral replication, alteration of cellular components, and viral lysis.
The consequent alteration of cellular redox state is potentiated by the correlated decrease of antioxidant and energetic reserves.
The alteration of cellular functions by anchoring macromolecules to specified organelles may reveal a new area of therapeutic potential and clinical treatment.
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