Sentence examples for alterations not only from inspiring English sources

These alterations not only prevent the formation of a hexamer but also distort the active site geometry resulting in a dimeric form of FabZ that is incapable of substrate binding.

It is likely that the selection of cell clones and their adaptation to various culture conditions may involve alterations not only in cellular machinery directly related to the selected marker or adapted behavior, but also those which may or may not be essential for selection or adaptation.

These alterations not only support the idea that senescence is preceded by an irreversible G1 arrest [30], [36], but also are reminiscent of a common function of herpesviral immediate-early genes, namely to halt cell cycle progression in G1 [18].

These combinations may lead to alterations not only in cellular metabolism but also in survival signal [ 122, 123].

Moreover, biometal alterations not only occur in the central nervous system (CNS), but also peripherally in NCL affected animals.

We now analyzed the entire set of RECQL5-dependent genomic alterations (not only recurring events) to establish whether the associations were generally observed.

If an alteration not only fixes the problem at hand but also allows the research programme to make a novel prediction, then the alteration is said to be progressive.

We confirmed that the epigenetic alteration not only of the CpG sites within the CpG island located on the promoter region of exon 1, but also of those distributed throughout the gene, exhibit a relationship with depressive symptoms.

TP53 is unique among tumor suppressor genes because its alteration not only results in loss-of-function of the product, but also generates a range of mutants demonstrating a gain-of-function phenotype.

In this elegant study, the authors show that MRI signal alterations are not only specific to c-MET activation but they are also dose dependent, as injection of HGF at 7 and 170 ng/g body weight resulted in signal alterations of 5 and 30% respectively.

Platelet-induced EMT-like alterations were not only observed at the transcriptome level but also morphologically.