Sentence examples for alterations may provide from inspiring English sources

In the era of tumour profiling, targeting molecular alterations may provide an opportunity for new therapeutic approaches.

Our findings, which reveal molecular linkages between starvation signals and reproductive alterations, may provide a basis for understanding energy reallocation mechanisms, as the mgl-1 deletion mutant exhibited more severe reductions in lifespan and fat accumulation than did wild-type animals under starvation conditions.

Epigenetic alterations may provide an explanation in these cases.

These in vitro alterations may provide the foundation for further assessment during in vivo assessment.

DNA methylation, along with other epigenetic alterations, may provide the link between environmental factors or intrauterine exposure and complex disorders.

These metabolic alterations may provide a biochemical basis for developing new therapeutic strategies to effectively kill TBNC by glycolytic inhibition.

As overexpression of Tfam delayed neuronal cell death following transient forebrain ischemia in mice, we believe that studying the benefit of increased Tfam expression on mitochondrial dysfunction including mtDNA alteration may provide a therapeutic target for fighting against RGC degeneration in ischemic retinal injury.

Therefore, we hypothesised that, if HR deficiency leaves a footprint of genomic alterations, LOH may provide a more stable record of those changes compared with CN variants.

The present study provides evidence that AT2 and AT4 receptors have opposite effects on vascular alteration caused by streptozotocin-induced diabetes in mice, a finding that provides new light on the complex role of the renin-angiotensin system on the diabetes-induced vascular alteration, and may provide new therapeutic tracks for optimizing vascular prevention in diabetes patients.

These alterations may also provide novel drug targets [ 21, 23, 25, 36, 40– 40].

Notably, the 'passenger' mutations, most of the alterations, may not provide growth advantage per se, but could cause resistance to therapy in a subset of cells, which can dominate the tumor next.