Sentence examples for alterations may contribute from inspiring English sources

In conjunction with altered mitochondrial function and motility, tubulin cytoskeleton alterations may contribute to the accumulation of protein aggregates and autophagic vesicles, and/or associated substrates, as observed in our sPD cybrids model.

TOP2A alterations may contribute to pathogenesis in HER2+ breast carcinomas by altering sensitivity to anthracyclines [ 31].

In these tumours with an altered control of genomic stability, accumulation of chemotherapy-induced genetic alterations may contribute to cell death and account for complete response.

These structural and functional alterations may contribute to the cognitive deficits seen in infants at risk for CH.

These alterations may contribute to immune modulation of the clinical phenotype of marrow failure in MDS, and may have to be considered when designing DC-based immunotherapeutic strategies for MDS.

These findings suggest that PICALM is required for cellular cholesterol homeostasis and point to a novel mechanism by which PICALM alterations may contribute to disease.

This alteration may contribute to incorrect identification of a vertebral segment, leading to wrong-level spine surgery and poor correlation with clinical symptoms.

Such "wiring" alteration may contribute not only to the behavioral deficits associated with this pharmacological model, but also to the disease pathogenesis.

Therefore, it is possible that epigenetic alteration may contribute to the increase of LRP6 protein content/phosphorylation by HNE.

This alteration may contribute to increasing neuronal excitability in the BNST and anxiety in the stressed rats.

Identifying relevant genetic variants or single nucleotide polymorphisms (SNPs) in genes intimately linked to various neurobiological pathways, whose alteration may contribute to suicidal behaviour, may provide insight into the etiological processes that underlie suicidal behaviour and identify novel biological therapeutic targets.