The phrase "alterations is associated" is not correct in standard written English.
It should be "alterations are associated" to agree in number with the plural noun "alterations."
Example: "In this study, alterations are associated with various environmental factors."
Alternatives: "changes are linked" or "modifications are connected."
Microcirculatory perfusion is also altered in patients with cardiogenic shock [ 49], and the evolution of these alterations is associated with outcome [ 50].
The expression of such morphological alterations is associated with genomic instability.
In addition to genetic changes, the occurrence of epigenetic alterations is associated with accumulation of both genetic and epigenetic events that promote the development and progression of human cancer.
Persistence of these alterations is associated with poor clinical outcome even if macrohemodynamic derangements have been corrected (see below).
After an acute disease, recovery of the muscle alterations is associated with an improved global functioning and quality of life [ 15].
The fact that the development of vascular alterations is associated with stroke and unfavorable outcome underlines its importance for the course of the disease.
None of these genetic alterations were associated with altered probability of relapse regardless of the presence/absence of IKZF1 deletion (Table S3).
These alterations are associated with loss of plasma membrane association of E-cadherin, a key regulator of epithelial intercellular adhesion.
The assessment of altered retinal blood vessels is important, since blood vessel alterations are associated with many retinal and systemic diseases including diabetes mellitus and hypertension [14], [15].
Using these devices, investigators have reported that the microcirculation is markedly altered in sepsis, alterations are more severe in nonsurvivors, and persistent microvascular alterations are associated with development of multiple organ failure and death [14 17].
