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Whether this occurred through alterations in the timing or strength of expression could not be established with the two time points considered in this study.
We next performed fetal thymic organ cultures to determine if this alteration in development is due to alterations in the timing of development of these cells.
Our data demonstrate that significant variation in leg size can result from alterations in the timing and duration of expression of a single gene.
Measuring MPS IIIB mice using real-time locomotor monitoring during the progression of lysosomal storage, we found alterations in the timing of daily locomotor activity at the earliest ages tested.
Less work has examined the impact of single alterations in the timing of the LD cycle [34], even though these phase shifts disrupt the rhythms in clock gene expression within the SCN [35], [36] and between the SCN and peripheral oscillators [37].
Our results confirm that SNPs at this locus are also associated with subtle effects on tooth development, including alterations in the timing of tooth eruption.
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An alteration in the timing of capacitation appears to be the cause for fertility reduction and the occurrence of small-sized and dead offspring.
Interestingly, the alteration in GI expression did not result in a dramatic alteration in the timing of the floral induction (Additional file 8).
Alterations in the correct timing, intensity, and balance of expression of proinflammatory versus anti-inflammatory cytokines by monocytes result in pathologic modulation of the inflammatory response.
However, with regards to cytoplasmic Ca2+ signals induced by insulin we found no alterations in the shape, timing or intensity in hypertrophic cardiomyocytes.
The delay in detachment of as1 medial sepals may represent an alteration in either the timing of abscission zone specification or of the subsequent activation of cell separation.
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