Sentence examples for alterations in the organization from inspiring English sources

dcc +/− mice exhibit selective alterations in the organization and function of the mesocortical DA circuit and appear to be protected against schizophrenia-like symptoms.

As a result we found that alterations in the organization of synaptic microtubules correlate with reduced protein levels in the microtubule associated protein futsch/MAP1B.

However, we saw no overt alterations in the organization of actin or microtubules in MiTMAB-treated neurons (data not shown), apart from the failure of migrating neurons to resolve their trailing processes at the cell rear.

In support of this idea, it was previously described that NMJ defects similar to TBPH loss of function were found in several other mutants that induce alterations in the organization of the microtubules (MT) at the synaptic terminals [24], [25].

This entire process is mainly supported by the underlying presynaptic cytoskeleton and induced us to hypothesize that alterations in the organization of these structures might explain the morphological defects observed in TBPH mutant alleles.

The evident defects in completing cytokinesis and their multiple attempts to divide led mutant cells to exhibit dramatic alterations in the organization of ciliary rows as confirmed using an antibody against centrin (Figure 4F and G, compare with D and E).

On the other hand, we did noticed alteration in the organization of actin filaments in LMP1 expressing cells which is consistent with the previous studies published by Dawson and colleagues who also showed actin filament remodelling following LMP1 expression in 3T3 fibroblasts [17].

The laminar organization in the dorsal spinal cord of Entpd3 -/- mice, as revealed by staining for CGRP and PKCγ and binding of IB4, was indistinguishable from that of WT mice, suggesting that there was no alteration in the organization of primary afferents or spinal neurons in the dorsal horns of mice that lack ENTPD3.

Alterations in the left right organization of the internal organ positioning such as situs inversus and situs ambiguous are observed in 50% of PCD patients (then called Kartagener's syndrome) and can be explained by dysfunctional nodal cilia during early embryogenesis.

Activity-dependent alterations in the spatial organization of the genome can regulate transcriptional activity related to neuronal plasticity.

Age related changes in the lacrimal gland are associated with alterations in the structural organization and functional response in the gland of diverse mammalian species.