The phrase "alterations in the development" is correct and usable in written English.
It can be used when discussing changes or modifications that occur during a developmental process, such as in biology, education, or project management.
Example: "The researchers noted several alterations in the development of the species due to environmental changes."
Alternatives: "changes in the development" or "modifications in the development".
Recent studies have shown that developmental exposure to genistein can cause alterations in the development of female reproductive tract of the rodent, including altered estrous cyclicity, altered ovarian function, subfertility, and infertility (Jefferson et al. 2005; Kouki et al. 2003; Levy et al. 1995; Nikaido et al. 2004).
The association between in vivo and post mortem findings will clarify the temporal dynamics of pathophysiological alterations in the development of preclinical AD.
All male fish were then sacrificed and analyzed for plasma vitellogenin, developmental changes in gonadal tissues, alterations in the development of secondary sexual characters, morphometric changes, and changes to reproductive behavior.
These data indicate that cardiac growth suppression or enhancement caused by nutritional manipulations may be mediated, in part, through alterations in the development of neuronal input to the tissue, and that similar factors influence survival during hypoxic stress.
Especially alterations in the development of brain, neural crest derivatives, and blood, which are the most sensitive to p53 upregulation, can be easily misinterpreted.
Fluoroquinolone residues have also been found in avian scavenger eggs and are associated with severe alterations in the development of embryo cartilage and bones that could preclude embryo movement and subsequently normal development, pre-hatch position and successful hatching [12].
The most striking finding of this study is the observed link between the physiological response to microbial infection and alterations in the growth, development and differentiation of D. melanogaster larvae and adults.
It has been proposed that an alteration in the development and/or composition of the microbiota may disturb the relationship between microbes and the immune system.
The very low hatching rate detected after the 12 h treatment was probably due to an alteration in the development of Artemia embryos.
In addition, prenatal exposures to environmental agents such as bisphenol A or dioxin results in alteration in the development of the mammary gland that may predispose to the development of cancers later in life.
In summary, our data demonstrate for the first time that promoter methylation-mediated downregulation of DKK3 expression is a frequent and tumour-related epigenetic alteration in the development of human breast cancer.
