Sentence examples for alterations in the coding from inspiring English sources
No other alterations in the coding region of FOXL2 gene were detected.
We therefore assume that some of the dominant alterations in the coding content of RTBV sORF 1 that occurred on passage of the chimeric virus in turnip plants might have slightly modulated elongation or termination rates of sORF 1 translation that controls shunt-mediated polycistonic translation on viral pgRNA.
Calculating that one third of these mutations shall fall on each of the three positions of a triplet codon, and further that mutations in the first and second positions shall be productive, and those in the third position, silent, one arrives at a number of 90 alterations in the coding sequences of this tumor cell.
None of the variants result in nonsynonymous alterations in the coding region of CSTF.
Still, we did not identify any synonymous sequence alterations in the coding regions assessed so random non-selected alterations are infrequent.
However, all too often, it is assumed that only genetic alterations in the coding sequences, that is, at exons, have an impact on the clinical course of the disease.
Apart from genetic alterations of proteins, alterations in the miRNA coding regions were shown to affect the regulation of DNA repair [ 26, 27].
Direct sequencing of the bands showing mobility shifts revealed that they were due to four previously described nucleotide alterations in the WWOX coding region.
Given that the cardiovascular system is a main target of DLC toxicity in all vertebrates [ 48], it is reasonable to propose that alterations in the cathepsin coding sequence could contribute to existing differences in DLC sensitivity.
This can be due to additional alterations in the EGFR coding sequence, such as small insertions or deletions in exon 20 and rare mutations co-existing with classical activating mutations.
Several genetic alterations in the genes coding for xenobiotic-metabolising enzymes (XMEs), DNA repair, cell cycle regulation and apoptotic pathway confer a low-penetrance genetic susceptibility to tobacco carcinogens (Kotnis et al, 2005).
