K8/K18 variants may also affect organelle function, as seen in K8 knockout mice, which exhibit altered mitochondrial shape, localization, and alterations in several mitochondrial proteins (Toivola et al. 2005).
Concentrations of 102 metabolites were found to be significantly altered in HE patients: metabolotypes displayed alterations in several major metabolite classes such as ammoniac, bile acids, but also amino-acids, acylcarnitines, and nucleosides.
While the introduction of any single NZM2410-derived locus has not been shown to recapitulate complete disease, the presence of both the Sle1 locus and the Sle3 locus on the B6 background results in severe glomerulonephritis, reinforcing the notion that multiple genetic alterations in several cell types may be necessary to drive lupus pathogenesis [ 28].
(Graduate students register for 252H). Global change is leading to significant alterations in several environmental factors, including temperature, ocean acidity and oxygen availability.
(Graduate students register for 281H). Global change is leading to significant alterations in several environmental factors, including temperature, ocean acidity and oxygen availability.
Breathing represents one of the vital functions of the organism, and its unbalance causes some series of alterations in several organs and systems.
Papillary thyroid carcinomas (PTCs) are associated with alterations in several proto-oncogenes related with nervous system development and function, such as TrkA and RET, which are commonly rearranged in these carcinomas.
By searching the inherited rare damaging or loss-of-function (LOF) variants and common susceptible alleles from three classes of schizophrenia candidate genes, we were able to distill genetic alterations in several schizophrenia risk genes, including GAD1, PLXNA2, RELN and FEZ1.
Our study may serve as a baseline investigation of motor-cortex alterations in several shoulder pathologies.
Memory deficits in mild cognitive impairment may be linked to functional alterations in several specific brain regions both inside and outside the medial temporal lobe.
Several studies indicated that migraine patients have tract-specific alterations in several white-matter tracts as compared to controls [1-12].
