Sentence examples for alterations in parallel from inspiring English sources

Sepsis induced an increase in the expression/activation of TLR4 and its downstream signaling JNK and IKK/NF-κB activation, and blunted insulin-induced insulin signaling in liver, muscle and adipose tissue; atorvastatin reversed all these alterations in parallel with a decrease in circulating levels of TNF-α and IL-6.

We aimed to describe these alterations in parallel to traditional renal and acid base parameters.

Sepsis leads to severe intestinal epithelial damage with a decrease in claudin 2 and occludin protein expression; probiotic pretreatment reversed these alterations in parallel with an increase in Hsp72 and Hsp25 activation.

As a first alteration, in parallel with the rapid increase in urinary output, urinary [Na+] constantly increased up to a value close to plasma [Na+] (about 142 mEq/L, as average).

This alteration, in parallel with increased SP NFD in tracheal smooth muscle, indicates that SP may be involved.

CcRCC is an example of a cancer, where a high rate of genomic alterations occurs in parallel to inactivating mutations and deletions of histone modifiers, such as SETD2 (Cancer Genome Atlas Research, 2013; Sato et al., 2013).

The objective of the current study is initially to use our cohort of 429 conservatively managed prostate cancer cases to assess the potential clinical significance of ETV1 gene alterations and in parallel to assess the relative frequency of each of the known ETV1 fusion partners.

Here we present a novel computational methodology, ENVE (Extreme Value Distribution Based Somatic Copy- Number Variation Estimation), which robustly detects tumor-specific copy-number alterations in massively parallel DNA sequencing data without the need for complex parameter choices or user intervention.

Conceivably therefore, if Ca2+ release from ER is altered with aging, this alteration may develop in parallel with altered Ca2+ influx (Clodfelter et al., 2002).

During breast tumor initiation and progression, the mammary microenvironment undergoes a number of dynamic and regulated alterations that occur in parallel to transformation13.

Taken together, these examples illustrate the link of collateral sensitivity to the complex genetic or transcriptional alterations that occur in parallel during the acquisition of the MDR phenotype.