Sentence examples for alterations in normal from inspiring English sources
As suggested by Borsook et al. (2012), Migraine is associated with alterations in normal homeostatic mechanisms (e.g., altered sleep, abnormal autonomic function).
About: Detect rare or de novo copy number alterations in normal DNA samples.
Simon-Sanchez, J. et al. Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals.
Glioblastoma is the most common and deadly brain tumor, possibly arising from genetic and epigenetic alterations in normal astroglial cells.
AGE modification of proteins may lead to alterations in normal function by inducing cross-linking of extracellular matrices.
In the filamentous fungus Neurospora crassa the H3K27me2/3 mark is principally subtelomeric covering ≈7% of the genome, and its loss results in telomere mislocalization and alterations in normal chromosome conformation42.
Multicontrast analysis was used to assess for microstructural alterations in normal-appearing (NA) tissue and lesions.
Even more thought provoking is the data published by Moinfar and colleagues [ 17], who demonstrated the presence of concurrent and independent genetic alterations in normal-appearing stromal and epithelial cells located either in the vicinity of or at a distance from the foci of DCIS or IDC.
Alteration in normal colonic pH and bacterial picture leads to incomplete release of drug from the designed delivery system.
Interestingly, some gene polymorphisms were associated with a lower methylation of the CpG islands examined, thus suggesting that genetic factors can influence this epigenetic alteration in normal colorectal mucosa [13].
However, whether this methylation-driven gene silencing mechanism represents a potential field effect due to an unidentified molecular alteration in normal mucosa or the expression of pre-existing multiple hyperplastic polyps from which CRC arises through the serrated pathway [38], as it has been recently suggested [32], remains unknown.
