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The prominent histological alterations in mouse placenta heavily infected with P. berghei-GFP resemble those described for acute P. falciparum malaria in humans [57], and future lines of research will clarify whether pathogenesis components, already identified in humans, have their counterpart in this model of severe malaria in pregnancy.
Nigam et al. [ 150] demonstrated the effects of lupeol on DMBA-induced alterations in mouse skin.
Eighty-four miRNAs have significant expression alterations in mouse brain, whereas only 56 miRNAs have significant expression alterations in the liver.
Overall the results of the present study show that administration of CPF in late gestation results in early behavioral alterations in mouse pups.
Likewise, in this study, alterations in mouse circulating levels of 5′ tRNA halves derived from specific tRNA isoacceptors were associated with aging and dwarfism.
In our studies we therefore analyzed the dynamics of H3K9me2 and H3K4me3 methylation along with DNA methylation alterations in mouse, bovine and rabbit zygotes.
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Papadopoulou, A. S. et al. Deficiency of the miR-29a/b-1 cleadsr leads to ataxic features and cerebellar alterations in mice.
Chronic treatment with epigallocatechin gallate restored these behavioral and biochemical alterations in mice.
Present study highlights the involvement of nitric oxide mechanism in the protective effect of imipramine and venlafaxine against acute immobilization-induced behavioral and biochemical alterations in mice.
The present study was designed to investigate the nitric oxide mechanism in the protective effect of imipramine and venlafaxine against acute immobilization stress-induced behavioral and biochemical alterations in mice.
Our studies have taken advantage of available technologies for producing genetic alterations in mice to study the physiology of these systems.
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