Sentence examples for alterations in less from inspiring English sources

Normalization of probe signals to reference probes could not be performed due to genomically unstable genomes, which also displayed alterations in less frequently unbalanced genomic regions.

On average, all genomic signatures of known cancer drug targets were significantly altered in 20% of cancer samples; meanwhile, putative non-drug targets showed the alterations in less than 8% of samples (Additional file 2).

[ 25] However, it is not known whether these phenotypic alterations occur in less severely ill cirrhotic patients (without SIRS) in association with endotoxaemia, and if present whether they contribute to functional T cell impairment.

We did not identify large rearrangements encompassing TP53, which is in line with previous reports of low prevalence of such alterations, encountered in less than 5% of LFS/LFL families [ 24, 25].

Tumour cells develop resistance to chemotherapy or radiotherapy over time via genetic alteration resulting in less effective treatment.

This alteration can result in less energy availability which is most commonly expressed as fatigue.

The neurochemical alterations in mania are less clearly understood, but it is well established that drugs effective in the treatment of mania are those that antagonize dopamine and serotonin.

By contrast, epigenetic alterations in metastases are less characterized than genetic changes in primary cancers.

In contrast, epigenetic alterations in metastasis are less well characterized than these genetic changes [ 9, 14].

Most attention in the dialysis literature has been directed to alterations in ultradian (periods less than 20 h) and circadian (periods between 20 and 28 h) rhythms [ 1].

Although some data indicate that the stromal compartment, when microdissected from human breast cancers, exhibits genetic alterations (Eng et al, 2009), the proportion of karyotypic alterations in fibroblasts remain less frequent than in cancer cells (Qiu et al, 2008).