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Thus, the dysregulation of Hsp27 consists of both the changes in cell population expressing this gene and the alterations in expression level.
Prlf2 expression was not altered in hypothalami of MECP2-Tg or Mecp2-null mice, thus alterations in expression of this gene are not global in the brain (19).
Cocaine-induced alterations in expression of c-fos and preprodynorphin mRNAs measured by TaqMan® were confirmed by ribonuclease protection assay.
Prostate cancer development and progression are associated with alterations in expression and function of elements of cytokine networks, some of which can activate multiple signaling pathways.
The present study revealed alterations in expression of 172 genes involved in apoptosis, inflammation, heart function, and growth.
Furthermore, microarray analysis revealed that 5-Aza-2-deoxycytidine treatment leads to alterations in expression of several developmentally regulated genes.
Alterations in expression between adjacent time points across the entire time series were characterized using the trajectory clustering algorithm [14].
Over the past decade, alterations in expression of ALCAM have been reported in several human tumors and recently in renal carcinoma and in neuroblastoma primary tumors [33].
This is consistent with previous reports of no alterations in expression of other isoforms in brain tissue from PKCε-deficient mice [21].
These include e.g. altered methylation of individual gene promoters [2], [3], [4] or genome-wide changes [5], as well as alterations in expression of microRNAs [6].
In addition, no alterations in expression of these markers were observed when spleens were obtained from rats at 7days following LTx (Fig. 4B).
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