Sentence examples for alterations in component from inspiring English sources

Understanding the role of these pathways in cancer biology has been enabled through the characterization of alterations in component pathway nodes including amplification of receptor tyrosine kinases like Her and EGFR, and genetic changes in PTEN, PIK3CA, AKT, KRas and BRAF, all of which have been shown to contribute to the cancer phenotype.

Virus-induced alterations in components of grass pollen have the potential to alter the allergenic potency.

Levy, L. & Hill, C. S. Alterations in components of the TGF-beta superfamily signaling pathways in human cancer.

Additional studies, not discussed in this review, suggest that alterations in components of telomeric chromatin can also influence either the types of recombination events that occur at the telomere (Teng et al., 2000) or the frequency with which the survival pathway appears (Chandra and Lundblad, unpublished observations).

In addition, alterations in components of the Research Domain Criteria negative valence systems, including neural processing of sadness, loss, and threat, have been observed in risk for depression, though effects appear to be more task and method dependent.

Interestingly, a subset of GBM with better outcome shows expression alterations in components of NOTCH pathway [30].

Thus, genetic alterations in components of the Wnt pathway appear to affect female more than male mice.

In this context, the main objective of the present study was to investigate alterations in components of the autophagy pathway in DLB and in a-syn tg models.

Alterations in components of the Wnt pathway other than Lef1 may also have stronger skeletal effects in females as compared to males.

Alterations in components of the respiratory chain that affect reaction efficiency promote electron transport to oxygen and the generation of ROS [15].

Although the function of these structures in hypothalamic neurons is not known, it is interesting that there are a number of human diseases and transgenic mice in which alterations in components of the primary cilia are associated with obesity.