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The phrase "alterations in charged" is not correct in English.
It seems to be an incomplete or incorrect expression, possibly intended to convey changes related to something being charged, but it lacks clarity.
Example: "The alterations in charged particles affected the experiment's outcome."
Alternatives: "changes in charge" or "modifications in charge."
Exact(1)
Because the mutations in the apoE variants involve alterations in charged amino acids, nonionic urea was used as a denaturant rather than the ionic GdnHCl denaturant so that the contributions of electrostatic interactions were not suppressed.
Similar(59)
Implementation of negative charges on PEG due to modification with Ptyr led to an increased electrophoretic mobility, which was reduced after enzymatic degradation of the phosphate ester, most likely due to the alterations in charge distribution on the polymeric backbone.
Exceptionally, AtXI-J hadditionalnalterationsons in charge and polarity not present in the other sequences (residues underlined).
It is assumed that alterations in charge distribution in these amino acids may play a role in transition to a secondary structure.
These considerations and the predominance of defects in charge selectivity point to alterations in the negatively charged glomerular endothelial glycocalyx as the missing link.
These studies clearly show that depending not only on the number of chelate or dye groups, but also on their nature, alterations in hydrophobicity, charge, or conformation might be introduced, resulting in an altered behavior of the antibody conjugates in vivo.
Hyperoxia-induced alterations in the charge characteristics of ANXA1 were unchanged by RA recovery and were associated with elevated lung macrophage numbers.
These predictions were confirmed by experimental microelectrode measurements of stable Em over prolonged (>5-h) periods, despite alterations in glycocalyceal charge produced by varying extracellular [Ca2+].
We further visualized the electrostatic surface potential of these proteins to find out whether the noted differences in the pI of MIF/MDL proteins (Table 1) is reflected by prominent alterations in surface charge distribution.
The mathematical treatment of the glycocalyx was combined with the CD cellular model of Fraser and Huang (5, 7, 8), yielding a model that was used to predict the influence of alterations in glycocalyceal charge upon steady-state electrophysiological variables under a variety of conditions.
The synthetic modification on PEI was performed by emulating the influenza virus hemagglutinin, with an alteration in the charge density of Viromer particles to make their surface charge neutral [ 23].
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CEO of Professional Science Editing for Scientists @ prosciediting.com